Local resistance, on demand
Antibiogram software that turns your susceptibility export into empiric therapy answers
Drop in the export you already pull for the annual antibiogram. Read it back by every unit, every source and the full year, with empiric options ranked, in about a minute.
Your file is parsed in your browser and never uploaded. No card required.
Same selection, ranked
Empiric options for the filters you just set
Ranked by coverage: the share of every isolate in this selection that was susceptible to that agent. Counting it this way stops a drug tested only on gram positives from out-ranking a broad agent on a mixed population. Drugs tested on fewer than 30 isolates are left out rather than guessed at.
Sends only the computed matrix above, meaning organism, drug, %S and n. No rows, no dates, no identifiers.
Quarterly trend
Pick any tile in the matrix to plot that organism and drug pair across the four quarters.
Antimicrobe is a data analysis and surveillance tool. It is not a medical device, it is not FDA cleared, and it does not diagnose or prescribe. Empiric rankings are computed from the susceptibility data you provide and are for clinical review by qualified professionals. The bundled dataset is synthetic and contains no patient data.
01
The antibiogram is annual. Resistance is not.
A twelve-month export is pulled, de-duplicated by hand, pivoted, formatted and circulated as a PDF. By sign-off it describes last year, and nobody re-runs it.
02
One facility-wide number hides the ICU.
Blending outpatient urine with intensive care bloodstream isolates produces a figure that describes neither. The clinician who needs the unit-level number gets the average.
03
The cuts nobody has time for never get made.
Has Klebsiella pneumoniae against cefepime moved since the first quarter? Answering it costs another week of somebody's time, so the question stops being asked.
What changes
Current instead of annual, cuttable instead of blended, defensible instead of remembered
Re-run it whenever the file changes
The unit of work is the cut, not the annual report. A new export refreshes the trailing twelve months, and last quarter is one click from the full year.
Ask by source, unit and syndrome
Urine in the emergency department behaves nothing like respiratory isolates in the intensive care unit. Both are filters here, and each cut suppresses its own thin cells.
Show the rules next to the number
De-duplication, the reporting threshold and the treatment of intermediate results are printed under every matrix, so the output survives a pharmacy and therapeutics meeting.
Four steps
From a laboratory export to a report you can circulate
The method is the one your microbiology team already follows. The difference is that it takes a minute, it is repeatable, and every decision it makes is written on the page. There is more detail on how antimicrobial susceptibility testing data becomes an antibiogram.
- 01 Import the export you already produce Seven columns: patient key, collection date, specimen source, unit, organism, antibiotic and the S, I or R result. MIC values are used where they are present. Column names are detected, and you can override the mapping.
- 02 De-duplicate to the first isolate per patient One isolate per patient, per organism, per period, so a single heavily cultured patient cannot bend the report. The count before and after de-duplication is shown, not hidden.
- 03 Apply breakpoints and the reporting threshold Your reported interpretation is used as it stands, or MIC values are read against a CLSI or EUCAST version. Cells under the threshold are marked rather than quietly dropped.
- 04 Publish the matrix, the ranking and the receipt Export to CSV, print to a clean page, and carry the rule receipt with it so the committee can see exactly what produced each number.
Anatomy
Four things a cell has to tell you
Everything in the matrix above is one of these four states. Read them once and the whole report reads faster, including the parts that are deliberately not reported.
A percentage, and its base
92 percent of the 418 isolates tested were susceptible. The count is part of the number, because 92 percent of 418 and 92 percent of 12 are not the same claim.
Colour carries the decision
The ramp runs pale to deep as susceptibility rises, so a row of pale tiles is a drug class you should stop reaching for first in this population.
Below the threshold, and marked
Seventeen isolates is not a rate. The black tile says the cell exists and is not being reported, which is more honest than an empty square.
Not on the panel
The laboratory did not test that organism and drug pair, often because of intrinsic resistance. A dash means no data, never zero percent.
Input to output
Three rows in, one cell out
There is no model in the middle and nothing to take on faith. The transform is counting, under rules you can see and change. Here is the same arithmetic the builder runs on every organism and drug pair in your file.
Patient 4471 appears twice. Under the first isolate rule the second row is dropped before anything is counted, which is where most hand-built antibiograms go wrong.
| patient | date | source | organism | drug | sir |
|---|---|---|---|---|---|
| 4471 | 2026-03-04 | Urine | E. coli | CIP | S |
| 4471 | 2026-05-19 | Urine | E. coli | CIP | dropped |
| 4488 | 2026-03-06 | Urine | E. coli | CIP | R |
| 4502 | 2026-03-11 | Urine | E. coli | CIP | S |
2 susceptible / 3 first isolates
first isolate rule on
In a real file this cell would carry hundreds of isolates, and three would be suppressed.
For the pharmacy director
The report your program owes the committee, without the week it takes
The antibiogram is not optional work. It is an accreditation artefact, a stewardship input and the reference every empiric guideline in the building is built on. What is optional is spending pharmacist weeks assembling it by hand, and answering none of the follow-up questions.
- A dated report with its rules printed on it, ready to hand to a surveyor.
- The unit-level cuts your intensivists ask for, produced while they wait.
- A price on the website, so procurement can be started rather than scheduled.
More on the reporting side in antibiotic stewardship program software and Joint Commission antimicrobial stewardship reporting.
Honest comparison
What you are choosing between
Only facts you can check on each vendor's own site in five minutes. WHONET is genuinely good software and it is free. The enterprise suites do far more than this does. The question is which one matches the job you have.
| Excel and one pharmacist | WHONET | Enterprise surveillance suites | Antimicrobe | |
|---|---|---|---|---|
| What it is | A pivot table built once a year | Free desktop software from the World Health Organization for managing and analysing susceptibility data | Hospital-wide surveillance platforms with feeds from the electronic health record and laboratory system | Browser software that turns a susceptibility export into cuttable antibiograms |
| Published price | None, but 20 to 60 pharmacist hours a year | Free | Not published. Pricing requires a sales conversation | $249 to $2,400 a month, on the pricing page |
| Install | Excel | Windows desktop install and data configuration | IT project with interfaces | None. It runs in the browser |
| Time to the first number | Days to weeks | After the data mapping is configured | After the integration is live | One export, then about a minute |
| Cuts by unit, source and period | One cut, usually facility wide | Yes, once configured | Yes | Yes, as filters |
| Rules visible on the output | Whatever the analyst remembers | Configurable | Varies by product | Printed under every matrix |
Switching from WHONET or a spreadsheet is covered honestly on the WHONET alternative page, including what you should keep doing in WHONET.
You might be thinking: this is a toy that does not know M39.
Then read the receipt under the matrix. It names the de-duplication, the threshold and the treatment of intermediate results that produced the numbers above it.
You might be thinking: I am not uploading patient data to a website.
You are not. The builder parses your file in the browser. Open the network tab and watch nothing leave.
You might be thinking: our numbers will be wrong without de-duplication.
They would be. That is why the first isolate rule is on by default and shows the count it removed.
Plans
The price is on the website
Four plans, published in full, because finding out what this costs should not require booking a call. Plans open as onboarding batches open, and the builder above stays free.
Lab
One facility, one microbiology team, the annual antibiogram done properly.
$249
per month, billed monthly
- 1 facility
- 25,000 isolates a year
- 2 seats
- Antibiogram engine with M39-style rules
- Cuts by source and period
- CLSI breakpoint set
- CSV and print exports
- Email support
Stewardship
RecommendedThe full cut matrix, quarterly trends and MDRO thresholds for an active program.
$749
per month, billed monthly
- Up to 3 facilities
- 150,000 isolates a year
- 8 seats
- Cuts by source, unit, period and syndrome
- Quarterly trend tracking
- MDRO watch with threshold alerts
- CLSI and EUCAST breakpoint sets
- Email support, one business day
Network
Several facilities compared side by side, fed by a scheduled export.
$2,400
per month, billed monthly
- Up to 12 facilities
- 750,000 isolates a year
- 25 seats
- Cross-facility comparison
- API and scheduled LIS export ingest
- Custom breakpoint sets
- Audit log
- Priority support and onboarding
Enterprise
Health systems with procurement, security review and an SLA.
Custom
priced on the conversation
- Unlimited facilities and isolates
- Unlimited seats
- SSO and SAML, SCIM, roles
- Full audit log
- BAA available
- Data residency options
- Invoicing and purchase orders
- SLA and a named onboarding contact
Prices in US dollars. No plan is charged today and no card is collected: plans open as onboarding batches open, and the antibiogram builder stays free either way. Enterprise items such as SSO, a business associate agreement and data residency describe what that plan includes, not a certification we already hold.
Mini glossary
Twelve terms this report assumes
Useful when a new analyst inherits the antibiogram, and when a committee member asks what the intermediate column is doing there.
- MIC
- Minimum inhibitory concentration: the lowest antibiotic concentration that stops visible growth of the isolate in vitro, read in doubling dilutions such as 0.5, 1, 2, 4 mg/L.
- Breakpoint
- The MIC or zone diameter value that separates susceptible from resistant for one organism and drug pair. CLSI and EUCAST publish and revise them, and they differ.
- %S
- The share of tested isolates reported susceptible. The denominator is the decision that matters: whether intermediate results sit in it changes every number on the report.
- First isolate rule
- Count each patient once per organism per analysis period, normally the first isolate. Without it, a few heavily cultured patients pull the whole antibiogram toward their resistance pattern.
- Intermediate and SDD
- Intermediate means the drug may work at higher exposure or at a body site where it concentrates. Susceptible-dose-dependent means susceptibility depends on the dosing regimen used.
- Cumulative antibiogram
- A periodic summary of susceptibility across all isolates in a period, organism by antibiotic, used to guide empiric therapy rather than to treat one patient.
- Empiric therapy
- The antibiotic started before culture and susceptibility results are back, chosen from the local pattern for that syndrome, source and unit.
- MDRO
- Multidrug-resistant organism. In practice the watch list is MRSA, VRE, ESBL producers, carbapenem-resistant Enterobacterales and resistant non-fermenters.
- ESBL
- Extended-spectrum beta-lactamase: an enzyme that inactivates most penicillins and cephalosporins, common in Escherichia coli and Klebsiella pneumoniae.
- CRE
- Carbapenem-resistant Enterobacterales: resistant to at least one carbapenem, which removes the drug class most teams rely on as the fallback.
- DOT
- Days of therapy, usually reported per 1,000 patient days present. The standard antibiotic use measure in United States stewardship reporting.
- SAAR
- Standardised antimicrobial administration ratio: observed antibiotic use divided by predicted use, published by the CDC through the NHSN antimicrobial use option.
Questions
Answered directly
The rest, including de-identification, multi-site work and what we do not do, is on the antimicrobial resistance software FAQ.
What data do you need to build an antibiogram?
Seven columns: a patient identifier, the collection date, the specimen source, the unit or location, the organism, the antibiotic and the S, I or R result. That is the same export you already pull for the annual report. MIC values are welcome and are used where present, but they are not required.
Does my data leave my browser in the demo?
No. The Antibiogram Builder on this site parses your CSV with the browser file API and computes every number locally in JavaScript. There is no upload, and no network request carries your rows. You can confirm it by opening the network tab before you pick the file.
Is Antimicrobe a medical device?
No. Antimicrobe is a data analysis and surveillance tool. It is not FDA cleared, it does not diagnose, and it does not prescribe. It computes susceptibility summaries from data you provide, for review by qualified professionals against your own guidelines.
Do you use CLSI or EUCAST breakpoints?
Both. If your export already carries an S, I or R interpretation, we use it as your laboratory reported it. Where MIC values are present, the Stewardship plan and above can reinterpret them against a chosen CLSI or EUCAST version, which is how you re-run last year under this year's breakpoints.
How do you handle intermediate and SDD results?
As a switch, not a hidden default. By default intermediate is counted separately and left out of the %S denominator, which is the common cumulative reporting choice. One toggle counts intermediate as resistant instead, and the rule receipt under the matrix always states which one produced the numbers on screen.
What is the first isolate rule, and can I turn it off?
It keeps the first isolate per patient, per organism, per analysis period, so one heavily cultured patient cannot skew the report. It is on by default and it is a toggle. The builder shows the isolate count before and after de-duplication, so you can see exactly what the rule removed.
Why suppress cells with fewer than 30 isolates?
Because a percentage on eleven isolates is noise that reads like a fact. CLSI M39 guidance is not to report an organism and drug combination with fewer than 30 isolates in a cumulative antibiogram. The threshold is a setting, and suppressed cells stay visible as a marked tile rather than disappearing.
Can I cut the antibiogram by unit and specimen source?
That is the point of the product. Source, unit, period and organism group are filters, so an ICU respiratory antibiogram and an outpatient urine antibiogram are two clicks apart rather than two projects apart. Suppression applies to each cut independently, because smaller cuts have smaller cells.
What does it cost?
From $249 a month for a single facility to $2,400 a month for a twelve-facility network, with Enterprise priced on the conversation. Every limit is published on the pricing page. There is no free plan, because the builder on this page is the free version.
What happens after I sign up?
You get a 6-digit code by email to confirm the address, and that is the whole sign-up. We then email you the next steps for getting your own susceptibility export in. Nothing is charged, and no card is asked for.
Start with your own export
See your own resistance picture, cut the way you actually work
Build the antibiogram on the synthetic sample dataset, or drop in your own CSV and watch it parse without leaving your browser. When you want an account, one email address is the whole sign-up.
Your file is parsed in your browser and never uploaded. No card required.